Clinical practice with antidementia and antipsychotic drugs: Audit from a geriatric clinic in India

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Clinical practice with antidementia and antipsychotic drugs: Audit from a geriatric clinic in India

Krishna Prasad, Himanshu Gupta, Srikala Bharath, Om Prakash,1 P. T. Sivakumar, C. Naveen Kumar, Geriatric Clinic and Services, and Mathew Varghese
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore – 560 029, India
1Department of Psychiatry, Institute of Human Behaviour & Allied Sciences, Delhi – 110 095, India
Address for correspondence: Dr. Om Prakash, Associate Professor of Psychiatry, Consultant in Adult and Geriatric Psychiatry, Department of Psychiatry, Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi – 110 095, India. E-mail: ni.oc.oohay@polawrihjrd
Copyright © Indian Journal of Psychiatry

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background:

Dementia is one of the most disabling disorders afflicting the elderly, with a staggering emotional and economic impact. Antidementia agents have been used for delaying cognitive decline. Antipsychotics are commonly prescribed for behavioral symptoms associated with dementia.

Objectives:

To explore the use of anti-dementing agents and antipsychotics used in patients with a diagnosis of dementia

Materials and Methods:

A retrospective chart review method; geriatric clinic of tertiary care setting.

Results:

The study sample included 51 consecutive patients with a diagnosis of dementia. The commonest subtype of dementia that was diagnosed was Alzheimer’s disease (45%), followed by Frontotemporal dementia (25%).The commonest antidementia drug that was used was donepezil, which alone was prescribed in 27 patients (52%). The commonest antipsychotic used was quetiapine, which was used in 24 patients (47%).

Conclusions:

The study found donepezil to be the most commonly prescribed antidementia drug and quetiapine to be the most commonly used antipsychotic in a tertiary care geriatric clinic, in a developing country. There is a need to study the cost-effectiveness of antidementia and antipsychotic drugs in patients with dementia, in developing countries.

———Read the full study at the NIH site or locally here as a PDF

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